In anticipation of the upcoming clash between Frosinone and Roma, manager Daniele De Rossi is expected to make several changes following their recent Europa League outing in Rotterdam. Alterations are foreseen primarily in defense, with Angelino set to reclaim the left-back position from Spinazzola, and Karsdorp poised to operate on the right flank.

In defense, Mancini is likely to retain his place, with a slight uncertainty surrounding the partnership alongside him, where Llorente and Huijsen are contending for the spot, with the latter marginally favored. Returning to the midfield from the start is Cristante, replacing Bove, alongside Paredes and Pellegrini. Upfront, Lukaku, who found the net against Feyenoord, is anticipated to lead the attack alongside Dybala and El Shaarawy.

In goal, Rui Patricio is set to reclaim his position, although Svilar remains hopeful of a breakthrough. Additionally, N’Dicka is back in contention, adding depth to the defensive options.

Meanwhile, Frosinone, under the guidance of former Roma manager Di Francesco, is expected to rely on the attacking trio of Kaio Jorge, Harroui, and Soule. In midfield, the pivotal role is entrusted to the former Giallorossi player Mazzitelli.

Here are the predicted lineups for the upcoming encounter:

Frosinone (4-3-3): Turati; Gelli, Monterisi, Okoli, Valeri; Mazzitelli, Barrenechea, Brescianini; Soule, Kaio Jorge, Harroui. Manager: Di Francesco.

Unavailable: Kalaj (to be assessed), Ghedjemis (returning 26th matchday), Marchizza (returning 30th matchday), Oyono (returning 26th matchday), Bonifazi (returning 27th matchday), Lusuardi (returning 26th matchday), Zortea (returning 26th matchday), Cuni (returning 26th matchday). Others: Pahic, Macej, Bidaoui.

Suspended: Romagnoli. Booked: Oyono.

Roma (4-3-3): Rui Patricio; Karsdorp, Mancini, Huijsen, Angelino; Paredes, Cristante, Pellegrini; Dybala, Lukaku, El Shaarawy. Manager: De Rossi.

Unavailable: Abraham (March). Others: Pagano, Oliveras, Pisilli.

Suspended: None. Booked: Kristensen, Llorente, Pellegrini.

Stay tuned for further updates and analysis as the matchday approaches.